5-Amino-1MQ 5mg is a research-use-only small-molecule compound supplied for qualified laboratory settings. Also known as 5-amino-1-methylquinolinium, 5-Amino-1MQ has been investigated in preclinical research primarily as an inhibitor of nicotinamide N-methyltransferase (NNMT).
Unlike many products within the research-peptide category, 5-Amino-1MQ is not a peptide. It is a quinolinium-based small molecule studied in experimental models involving NNMT activity, nicotinamide metabolism, cellular NAD+ availability, methyl-donor metabolism, and related biochemical pathways.
This product is intended strictly for in vitro research, analytical testing, and laboratory investigation. It is not intended for human or animal consumption, clinical use, diagnostic use, therapeutic use, or veterinary use.
Research Specifications
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| Product Name |
5-Amino-1MQ |
| Vial Quantity |
5mg |
| Compound Type |
Small-Molecule Research Compound |
| Research Classification |
NNMT Inhibitor |
| Primary Research Target |
Nicotinamide N-Methyltransferase (NNMT) |
| Chemical Family |
Methylquinolinium Compound |
| Also Known As |
5-Amino-1-methylquinolinium |
| Intended Use |
Laboratory Research Only |
NNMT Inhibitor Research
5-Amino-1MQ has been investigated as an inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in the methylation of nicotinamide.
NNMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA). Because this biochemical reaction intersects nicotinamide and methyl-donor metabolism, NNMT has become a research target in studies examining cellular metabolic regulation.
Published experimental work with 5-Amino-1MQ has demonstrated NNMT inhibition and reduced intracellular 1-MNA in cultured adipocytes.
NAD+ & Nicotinamide Pathway Research
NNMT research has attracted interest partly because nicotinamide participates in cellular pathways associated with nicotinamide adenine dinucleotide (NAD+) metabolism.
In experimental adipocyte models, researchers investigating 5-Amino-1MQ have reported changes in intracellular NAD+ and SAM measurements alongside inhibition of NNMT activity. These findings provide a biochemical framework for studying the relationship between NNMT, nicotinamide availability, methyl-donor metabolism, and cellular metabolic pathways.
These observations come from preclinical experimental systems and should not be interpreted as establishing clinical effects or therapeutic applications.
Cellular Metabolism Research
Laboratory research involving 5-Amino-1MQ has also examined NNMT inhibition in experimental models of adipocyte differentiation and cellular lipid metabolism.
Published cell-culture research has reported concentration-dependent changes in lipid accumulation in differentiating 3T3-L1 cells exposed to 5-Amino-1MQ. Additional studies have investigated NNMT inhibition in animal models and other experimental systems.
These findings are useful for understanding the compound’s role as an experimental NNMT research tool, but they do not establish outcomes in humans.
Small-Molecule Research Profile
5-Amino-1MQ is chemically distinct from peptide-based research materials.
Rather than consisting of amino-acid residues joined by peptide bonds, 5-Amino-1MQ is based on a methylquinolinium molecular scaffold. Its small-molecule structure and reported cellular permeability have made it useful in experimental investigations of intracellular NNMT activity.
The shorthand 5-Amino-1MQ may refer to material supplied in different salt forms. Because counterions affect molecular formula and molecular weight, those specifications should be interpreted according to the chemical form identified by applicable batch-specific analytical documentation.
Research Material & Documentation
5-Amino-1MQ 5mg is supplied as laboratory research material in a sealed vial.
Pinnacle Peptide Labs focuses on clearly labeled research compounds and batch-specific analytical documentation. Documentation may be included within the product gallery or made available for review where applicable.
Research Use Only
5-Amino-1MQ 5mg is intended strictly for laboratory research purposes only.
This product is not intended for human consumption, animal consumption, clinical use, diagnostic use, therapeutic use, veterinary use, or for the treatment, cure, mitigation, or prevention of any disease.
